Sievers Eclipse Bacterial Endotoxins Testing (BET) Platform
Veolia
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Compliant, consistent, conscious bacterial endotoxins testing
The Eclipse platform achieves automation and precision in BET assays without sacrificing compliance, reaction biochemistry, or footprint in the lab. Using embedded endotoxin standards and positive product controls (PPCs) with only <30 pipetting steps, the patented Sievers Eclipse microplate delivers automation without the complexity or expense of robotics.
Advantages
- Enables fully compliant, 21-sample assay setup in as little as 9 minutes
- Reduces Limulus Amebocyte Lysate (LAL) reagent use by up to 90%
- Meets all requirements of the harmonized pharmacopoeia: USP <85>, EP 2.6.14 and JP 4.01
- Embedded endotoxin for a standard curve and PPCs
- Provides segments for standard curves, samples, and PPCs
- Sensitivity down to 0.005 EU/mL
The Eclipse platform achieves automation and precision in BET assays without sacrificing compliance, reaction biochemistry, or footprint in the lab. Using embedded endotoxin standards and positive product controls (PPCs) with only <30 pipetting steps, the patented Sievers Eclipse microplate delivers automation without the complexity or expense of robotics.
The innovative Sievers Eclipse platform decreases assay setup time by up to 85% and reduces Limulus Amebocyte Lysate (LAL) reagent use by up to 90% while meeting all requirements of the harmonized pharmacopoeia: USP <85>, EP 2.6.14 and JP 4.01. Through groundbreaking technology, the Eclipse platform significantly decreases pipetting steps, reduces operator-to-operator variability, and simplifies assay setup. The Eclipse platform leverages precise microfluidic liquid handling and embedded endotoxin to automate kinetic chromogenic assays. Throughput of 21 samples per plate is maintained without the complexity of robotics or the time and technique demands of a traditional assay.
- BET Method : Kinetic chromogenic
- Detection Mode : Absorbance
- Range : 0.005-50 EU/mL
- Precision : ≤ 15% CV onset time
- Accuracy : 50-200% of actual
- Sample Type : Aqueous, injected by pipette
- Calibration : Up to 12 months
- Analysis Time : Up to 2 hours
- Outputs : Digital via USB
- Display : OLED
- Power Requirement : 100-240 Volts AC @40/60 Hz
- Fuses : T 8 A 250 VAC Fuse, size 5 x 20 mm. ONLY Littlfuse 218008 or Cooper Bussmann
- S506-8-R. Dimensions H: 17.5 cm (6.9 in); W: 35.1 cm (13.8 in); D: 50.3 cm (19.8 in)
- Medical device testing
- Pharmaceutical production testing
- Raw materials testing
Brochure
Sievers Eclipse Brochure (pdf / 8,52 MB)